publications

2020

Merkel cell polyomavirus DNA replication induces senescence in human dermal fibroblasts in a Kap1/Trim28 dependent manner. Siebels S, Czech-Sioli M, Spohn M, Schmidt C, Theiss J, Indenbirken D, Günther T, Grundhoff A, Fischer N. MBio accepted January 29th 2020.

Epigenetic changes in Kaposi sarcoma-associated herpesvirus infection and associated diseases. Fröhlich J. and Grundhoff A. Seminars in Immunopathology, accepted January 2020

Epigenetic modulation in chronic hepatitis B virus infection. Dandri M. Seminars in Immunopathology, accepted January 2020.

Epigenetic crosstalk in chronic infection with HIV-1. Lange U, Verdikt R, Ait-Amar A, Van Lint C. Seminars in Immunopathology, accepted January 2020.

2019

A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment.

Günther T, Fröhlich J, Herrde C, Ohno S, Burkhardt L, Adler H, Grundhoff A. PLoS Pathog. 2019 Oct 31;15(10):e1007838. doi: 10.1371/j

The Ubiquitin specific Protease Usp7, a novel Merkel cell polyomavirus Large T-Antigen interaction partner, modulates viral DNA replication.

Czech-Sioli M, Siebels S, Radau S, Zahedi RP, Schmidt C, Dobner T, Grundhoff A, Fischer N.

J Virol. 2019 Dec 4. pii: JVI.01638-19. doi: 10.1128/JVI.01638-19.

2018

CRISPR-Cas9-based Genome Engineering to Generate Jurkat Reporter Models for HIV-1 Infection with Selected Proviral Integration Sites.

Bialek JK, Walther T, Hauber J, Lange UC.

2017

Epigenetic manipulation of host chromatin by Kaposi sarcoma-associated herpesvirus: a tumor-promoting factor?

Günther T, Grundhoff A. Curr Opin Virol. 2017 Oct;26:104-111. doi: 10.1016/j.coviro.2017.07.018.